Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

07

2017-11

Nature Communications: Researchers from IPS-CAS and Freiburg University collaboratively discover the essential role of influenza A virus NP acetylation on viral growth and replication

On 2nd Nov, 2017, Researchers from Institut Pasteur of Shanghai, Chinese Academy of Sciences and Freiburg Universitypublish the recent research achievement in Nature Communications(Article)titled with “Role of influenza A virus NP acetylation on viral growth and replication” (doi:10.1038/s41467...

25

2017-10

Institut Pasteur of Shanghai discovered a novel mechanism that controls the quantity and quality of mature T cells

T cell maturation in the thymus requires both positive and negative selections. Positive selection has long been considered as a default process to allow the survival of thymocytes whose T cell receptors (TCR) display intermediate-affinity to self-peptide MHC complexes (self pMHC). In contrast, h...

08

2016-01

Researchers from IPS reveal a novel mechanism of HIV-1 mucosal infection (sexual transmission)

On December 30, 2015, the Journal of Virology published an advanced research work, entitled “Human mucosal mast cells capture HIV-1 and mediate viral trans-infection of CD4+ T cells”, from Jian-Hua WANG`s Lab, Institute Pasteur of Shanghai, Chinese Academy of Sciences. This work reveals a novel...On December 30, 2015, the Journal of Virology published an advanced research work, entitled “Human mucosal mast cells capture HIV-1 and mediate viral trans-infection of CD4+ T cells”, from Jian-Hua WANG`s Lab, Institute Pasteur of Shanghai, Chinese Academy of Sciences. This work reveals a novel...

08

2016-01

Researchers at Institute Pasteur of Shanghai reveal a novel mechanism for host factors regulating HIV-1 replication

On January 6th, 2016，the Journal of Biological Chemistry published an advanced research work, entitled “HIV-1 Nef-associated factor 1 enhances viral production by interacting with CRM1 to promote nuclear export of unspliced HIV-1 gag mRNA”, from Jian-Hua WANG`s Lab, Institute Pasteur of Shang...On January 6th, 2016，Journal of Biological Chemistry published an advanced research work, entitled “HIV-1 Nef-associated factor 1 enhances viral production by interacting with CRM1 to promote nuclear export of unspliced HIV-1 gag mRNA”, from Jian-Hua WANG`s Lab, Institute Pasteur of Shanghai,...