Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

22

2015-10

Researchers at Institut Pasteur of Shanghai identify a novel molecular pathway for the Th17 cells

The Journal of Biological Chemistry (JBC) published online the research conductedby Li Bin from Institut Pasteur of Shanghai, CAS and Lv Lin from rheumatism department of Fudan university Huashan hospital: TRAF5 Mediated K63-linked Polyubiquitination Plays an Essential Role in the Positive regul...The Journal of Biological Chemistry (JBC) published online the research conductedby Li Bin from Institut Pasteur of Shanghai, CAS and Lv Lin from rheumatism department of Fudan university Huashan hospital: TRAF5 Mediated K63-linked Polyubiquitination Plays an Essential Role in the Positive regul...

12

2015-10

Researchers at Institut Pasteur of Shanghai identify a novel molecular pathway for the regulatory of Treg cells

On October 1, Journal of Biological Chemistry published a research work online entitled “Poly(ADP-ribosyl)ation of FOXP3 Mediated by PARP-1 Regulates the Function of Regulatory T Cells” from a team of researchers led by Bin Li, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This stu...On October 1, Journal of Biological Chemistry published a research work online entitled “Poly(ADP-ribosyl)ation of FOXP3 Mediated by PARP-1 Regulates the Function of Regulatory T Cells” from a team of researchers led by Bin Li, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This stu...

12

2015-10

Researchers at Institut Pasteur of Shanghai identify a miRNA that promotes human Treg cell stability under inflammation

FOXP3+ Treg cells play a central role in maintaining the balance between immune tolerance and activation. Treg cells have a great plasticity and are not stable under inflammation and other physiological conditions. For instance, upon IL-6 stimulationTreg cells can lose the expression of FOXP3 and...FOXP3+ Treg cells play a central role in maintaining the balance between immune tolerance and activation. Treg cells have a great plasticity and are not stable under inflammation and other physiological conditions. For instance, upon IL-6 stimulationTreg cells can lose the expression of FOXP3 and...

29

2015-09

Researchers at Institut Pasteur of Shanghai reveal a novel function of HCoV-OC43 ns12.9 protein serves as a viroporin in morphogenesis and pathogenesis during human coronavirus infection

On September 2, Journal of Virology published a research work online entitled“The ns12.9 accessory protein of human coronavirus OC43 is a viroporin involved in virion morphogenesis and pathogenesis”from a team of researchers led by Bing Sun, Institut Pasteur of Shanghai, Chinese Academy of Scie...On September 2, Journal of Virology published a research work online entitled“The ns12.9 accessory protein of human coronavirus OC43 is a viroporin involved in virion morphogenesis and pathogenesis”from a team of researchers led by Bing Sun, Institut Pasteur of Shanghai, Chinese Academy of Scie...