Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

02

2018-03

Researchers of Institut Pasteur of Shanghai unveal the Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP

Endoplasmic reticulum (ER) stress response is mediated by dissociating with binding immunoglobulin protein (Bip) and controls cell fate. ER stress leads to the gene expression such as ATF4 and C/EBP homologous protein (CHOP).
　　B cell receptor (BCR) signaling is a physiologic ER stress trigger,...

01

2018-03

Institut Pasteur of Shanghai reveals that the chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

On February 26, Journal of Hematology & Oncology published the collaborative research work entitled "The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis" from Yan Zhang’s unit, Institute Pasteur of Shanghai, Chinese Academy of Sciences and Bin Zhou...

07

2017-12

Institut Pasteur of Shanghai reports that NLRP3 inflammasomemaintains intestinal homeostasis through modulating gut microbiota induced regulatory T cells

On Dec 1, 2017, The Nature Communications published anArticle research work entitled “Remodeling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis” from Guangxun Meng’s unit, Institute Pasteur of Shanghai, Chinese Academy of Sciences.
　　Inflammasom...

30

2017-11

Researchers of Institut Pasteur of Shanghai made an important progress in developing prophylactic HCV vaccine

Recently, researchers at Institut Pasteur of Shanghai, Chinese Academy of Sciences have made an important progress in developing prophylactic hepatitis c virus (HCV) vaccine, and published online an article entitled "A trivalent HCV vaccine elicits broad and synergistic polyclonal antibody respon...