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27
2018-04
Researchers from the Institut Pasteur of Shanghai developed recombinant protein based Zika vaccines
A joint research team led by Drs. Zhong Huang and Xia Jin at the Institut Pasteur of Shanghai (IPS), ChineseAcademy of Sciences (CAS), has recently completed preclinical studies of recombinant protein-based candidate Zika vaccines. This work was published as a research article entitled “Insect c...
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02
2018-04
Institut Pasteur of Shanghai reveals that recombinant ZIKV envelope protein elicited protective immunity against ZIKV in immunocompetent mice
On March 28th, 2018, Plos One published a research work entitled “Recombinant Zika virus envelope protein elicited protective immunity against Zika virus in immunocompetent mice” from Xia Jin’s unit, Institute Pasteur of Shanghai, Chinese Academy of Science.
Zika virus (ZIKV) is an em... -
29
2018-03
Researchers of Institut Pasteur of Shanghai revealed the function and mechanism of MLL5, an epigenetic regulator, in regulating antiviral immune response
On March 28th, 2018, Nature Communications published a research work entitled “MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation" from Yan Zhang’s unit, Institute Pasteur of Shanghai, Chinese Academy of Sciences. This work demonstrates that MLL5, ...
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02
2018-03Researchers of Institut Pasteur of Shanghai unveal the Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP
Endoplasmic reticulum (ER) stress response is mediated by dissociating with binding immunoglobulin protein (Bip) and controls cell fate. ER stress leads to the gene expression such as ATF4 and C/EBP homologous protein (CHOP).
B cell receptor (BCR) signaling is a physiologic ER stress trigger,...
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