Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

06

2010-05

The replication mechanism of Hepatitis C virus in cultured cells was revealed

In the presence of the N3H region and 3In the presence of the N3H region and 3’untranslated region(UTR)of JFH-1,a combination of A450S,R517K and Y561F was sufficient to confer HCV genome replication activity and virus production ability to J6CF in cultured cells(Fig. 2).Y561F was found to be enc...On April 30, 2010, the 《Plos pathogens》has published online the research progress on the replication mechanism of Hepatitis C virus (HCV) in cultured cells. This was a collaborative work done by Prof. Takaji Wakita’s group in NIH, Japan and Prof. Tetsuya Toyoda’s group in Institut Pasteur of ...

12

2010-01

High prevalence of Bocavirus infection among young children in Shanghai and co-infection with other respiratory viruses

High prevalence of Bocavirus infection among young children in Shanghai and co-infection with other respiratory viruses Since the first discovery of Human Bocavirus(HBoV)in 2005,the detection of HBoV was reported worldwide. It was significantly higher with symptoms of respiratory tract or gastroe...　　Since the first discovery of Human Bocavirus (HBoV) in 2005, the detection of HBoV was reported worldwide. The researchers in Institut Pasteur of Shanghai have examined extensively the virological and serological characteristics of human bocavirus infection to find out the correlation between...

28

2009-09

New diagnosis for A-H1N1 released by IPS

Influenza virus is the main cause of human respiratory infections, with high risk to trigger an influenza pandemic among vulnerable populations. The world is currently facing a new epidemic after the emergence, in April 2009 in Mexico, of a human-adapted swine H1N1 influenza A virus (A/H1N1/2...

10

2009-09

Progress in pathogenesis of SARS-CoV research by Prof. Sun Bing, Institut Pasteur of Shanghai, CAS (August 15, 2006)

　　Following to his discovery on a new protein—ORF-3a in SARS-CoV two years ago, Prof. Sun Bing, Principal Investigator in Institut Pasteur of Shanghai and his team further discovered the function of 3a protein as an ion channel regulating SARS-CoV release. The results are published at the rece...