Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

08

2013-05

IPS Researchers find novel molecular mechanism of MLL5 protein in cell cycle regulation

Mixed Lineage Leukemia 5 (MLL5) protein is a major member of histone H3K4 methyltransfereases, Its coding gene Mll5was located within chromosome band 7q22, which is frequently deleted in human acute myeloid leukemia. The previous study of Mll5 gene knockout mouse indicated that Mll5 gene is an im...Mixed Lineage Leukemia 5 (MLL5) protein is a major member of histone H3K4 methyltransfereases, Its coding gene Mll5was located within chromosome band 7q22, which is frequently deleted in human acute myeloid leukemia. The previous study of Mll5 gene knockout mouse indicated that Mll5 gene is an im...

28

2013-04

IPS researchers identified a new molecular pathway to control inflammation

On April 22, a study from the Key Laboratory of Molecular Virology and Immunology at the Institut Pasteur of Shanghai, Chinese Academy of Sciences（IPS-CAS） was released in the Journal of Biological Chemistry, entitled “TIP60 Positively regulates ThPOK-Mediated Repression of Eomesodermin in Hum...On April 22, a study from the Key Laboratory of Molecular Virology and Immunology at the Institut Pasteur of Shanghai, Chinese Academy of Sciences（IPS-CAS） was released in the Journal of Biological Chemistry, entitled “TIP60 Positively regulates ThPOK-Mediated Repression of Eomesodermin in Hum...

18

2013-01

Researchers elucidate neural-immunol regulatory mechanisms for postoperative cognitive dysfunction

Postoperative cognitive decline (PCD) complicates recovery from surgery especially in patients with the Metabolic Syndrome (MetaS). It is recently recognized that neuroinflammatory responses contribute to PCD that subsides when the inflammation resolves, but the exact neural-immunol regulatory me...

18

2013-01

Researchers elucidate neural-immunol regulatory mechanisms for postoperative cognitive dysfunction

Postoperative cognitive decline (PCD) complicates recovery from surgery especially in patients with the Metabolic Syndrome (MetaS). It is recently recognized that neuroinflammatory responses contribute to PCD that subsides when the inflammation resolves, but the exact neural-immunol regulatory me...