Viral Disease and vaccine Translational Research unit (Xia Jin)
Viral Disease and vaccine Translational Research unit was established in 2012 to fulfill two scientific objectives:
(1) To understand the interplay between human immune system and viral infections
(2) To develop novel vaccines based on new scientific knowledge and modern experimental technology.
To accomplish these objectives, we have developed four ongoing projects:
(i) Bioinformatics design and experimental testing of a subunit HIV vaccine comprised of multiple T helper cell epitopes;
(ii) Dissecting the role of each domain of dengue viral envelop protein at the induction of immune responses against dengue;
(iii) Bioinformatics design and experimental testing of a single dengue vaccine capable of eliciting tetravalent neutralization antibodies against multiple dengue virus serotypes;
(iv) Comprehensive mapping of T cell epitopes in HCV infected patients with or without spontaneous viral clearance.
While our research efforts are highly focused mostly of the time, their scopes and directions are subject to change with the advancement of science and alteration of global health priorities. Self- motivated students are welcome to join our research team.